BCG (Tuberculosis) Vaccine

    1. The graph below shows that immunization with BCG vaccine starting at school age (after 2 months of life) is associated with an increased risk of IDDM in Europe.     

2. Published Data from Quebec supports the ecological data from Europe (above)
that immunization with BCG vaccine starting after 1 year of life is associated
with an almost doubling of the risk of insulin dependent diabetes. The published
data from Quebec (Diabetes Care 20: 767-772, 1997) showed 14 of 249
diabetics (5.6%) were immunized with BCG after 1 year of life compared to 12
of 431 controls (2.78%).