Use sprite slices directly instead of prefabs

Hi,

is it possible to use tile sheet slices directly instead of creating a prefab for each tile (which is really annoying)?! I want to place the sprite directly via C#.

I plan on using different tile sheets (same tiles, different colors/look) and don't want to create prefabs manually for each tile for each sheet.

In plain C++ I would code something like (pseudo code of my older engine):

 window.draw(spritesheet1.subrect(0,64,0,64)) //Draw first tile onto the screen

This way I can easily exchange spritesheet1 with spritesheet2 and so on.