A problem with EditorWindow when run a script on launch (InitializeOnLoad)

I've got this warning when I use [InitialzeOnLoad] and call a script on my EditorWindow

The editor layout could not be fully loaded, this can happen when the layout contains EditorWindows not available in this project UnityEditor.WindowLayout:LoadDefaultWindowPreferences() (at C:/buildslave/unity/build/Editor/Mono/GUI/WindowLayout.cs:40)

My Code is

 static SettingUp()
 {
     Debug.Log("UNITY OPEN");
     EditorApplication.update += OnEditor;
 }

 private static void OnEditor()
 {
     EditorApplication.update -= OnEditor;
     SettingUp setup = CreateInstance<SettingUp>();
     setup.dosomething();
 }

The warning disappears when I commented out these two lines

 private static void OnEditor()
 {
     EditorApplication.update -= OnEditor;
     //SettingUp setup = CreateInstance<SettingUp>();
     //setup.dosomething();
 }

Any ideas? Please Help