Method that runs every time unity clears non-serializable properties

I have a code that needs add a handler to runtime scriptable object (singleton) to receive all invokes. but whenver the unity reloads the domain (or clears the non-serializable properties), the handler list is cleared and the instance stops receiving the invokes. Is there an event that runs AFTER the unity clears the non-serializable properties?

 myRuntimeScriptableObject.instance.AddHandler(new MyEditorOnlyHandler());