Do Network.Destroy and Network.Instantiate work in Single Player?

Do Network.Destroy() and Network.Instantiate() work when Network.peerType == PeerType.Disconnected? Or do I need to do something along the lines of this:

 if(Network.peerType == PeerType.Disconnected)
     Destroy(gameObject); // or Instantiate(gameObject);
 else
     Network.Destroy(gameObject);  // or Network.Instantiate(gameObject);