Single line if statement with many conditions or several single-conditioned if statements

I apologize that this is not exactly Unity related, but I could not find any information on this elsewhere.

I have been wondering for a long time now what is the best way to use if statements. You can see what I mean by that below.

A single line if statement(contains several conditions):

 if(X && Y && W && Z && G){
     Execute();
 }

 And Many statements inside a statement.

 if(X){
     if(Y){
         if(W){
             if(Z){
                 if(G){
                     Execute();
                 }
             }
         }
     }
 }

In the end they all do the same thing I suppose, but obviously the first example looks a bit more neat than the latter, but are there any performance benefits(or any benefits for that matter) using either of these two examples?

Thank you,

Yours faithfully.