How to change the color of predefine portion of the texture?

Sounds good.But i don't have idea about Sprite. can you please provide me some example link for reference? Thanks for quick reply :)

In attachement screenshot, it's just you to see how it looks loke. Here is a script to work with sprite. Sprite system is new, so there is not much tutorials on it. But sprite it's just a Texture2D in different maner.

 public static void PrepeareTexture2DAsSprite (string pathToTexture, bool isSpriteSingle = true, Sprite$$anonymous$$etaData[] spriteSheetData = null)
     {
     TextureImporter textureImporter = AssetImporter.GetAtPath (pathToTexture) as TextureImporter;
     TextureImporterSettings textureImporterSettings = new TextureImporterSettings ();
     
     textureImporter.textureType = TextureImporterType.Sprite;
     
     textureImporterSettings.spritePixelsToUnits = 1.0f;
     textureImporterSettings.mipmapEnabled = false;
     textureImporterSettings.readable = true;
     textureImporterSettings.maxTextureSize = 4096;
     textureImporterSettings.textureFormat = TextureImporterFormat.ARGB32;
     textureImporterSettings.filter$$anonymous$$ode = Filter$$anonymous$$ode.Point;
     textureImporterSettings.wrap$$anonymous$$ode = TextureWrap$$anonymous$$ode.Clamp;
     textureImporterSettings.npotScale = TextureImporterNPOTScale.None;
     textureImporterSettings.readable = true;
     
     textureImporter.SetTextureSettings (textureImporterSettings);
     
     AssetDatabase.ImportAsset (pathToTexture, ImportAssetOptions.ForceUpdate);
     AssetDatabase.Refresh ();
     
     if (isSpriteSingle)
     textureImporterSettings.sprite$$anonymous$$ode = (int) SpriteImport$$anonymous$$ode.Single;
     else
     {
     textureImporterSettings.sprite$$anonymous$$ode = (int) SpriteImport$$anonymous$$ode.$$anonymous$$ultiple;
     
     if (spriteSheetData != null)
     {
     textureImporter.spritesheet = spriteSheetData;
     }
     }
     
     textureImporter.SetTextureSettings (textureImporterSettings);
     
     AssetDatabase.ImportAsset (pathToTexture, ImportAssetOptions.ForceUpdate);
     AssetDatabase.Refresh ();
     }

Thanks a lot for for your valuable response :) but i am getting compile time error "he type or namespace name `Sprite$$anonymous$$etaData' could not be found. Are you missing a using directive or an assembly reference?" can you please help me for that ?

Sprite$$anonymous$$etaData it's UnityEditor namespace. Script, that i give you, it's Editor script. You can use

 #if UNITY_EDITOR
 ...
 #endif

to disable compiling editor part of script from behavior script.